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Sabrina Zappone

Fellowship
PhD Student Fellow
Molecular Microscopy and Spectroscopy
Research center
CHT@Erzelli
About

I studied Medical Biotechnology at the University of Modena and Reggio Emilia (Modena, Italy). In 2019, I moved to the University of York (York, UK) for a two-month traineeship. I obtained the M.Sc. in 2020 with a thesis entitled “Structural characterization of tardigrade Small Heat Shock Proteins”. After graduation, I joined the Molecular Microscopy and Spectroscopy group at the Istituto Italiano di Tecnologia (Genoa, Italy) as a fellow student. Since November 2021, I am a Ph.D. student in Bionanotechnology (Bioengineering and Robotics) at the University of Genoa (Genoa, Italy), in collaboration with IIT and under the supervision of Dr. Giuseppe Vicidomini. My research interests include the analysis of biomolecular dynamics, especially those involved in human diseases, using super-resolution microscopy tools.

Education

Title: Degree in Medical biotechnology (Personalized medicine)
Institute: University of Modena and Reggio Emilia
Location: Modena
Country: Italy
From: 2018 To: 2020

Title: Degree in Biotechnology
Institute: University of Modena and Reggio Emilia
Location: Modena
Country: Italy
From: 2015 To: 2018

Experience External

Title: Erasmus+ Traineeship
Institute: University of York
Location: York
Country: United Kingdom
From: 2019 To: 2019

Skills

Molecular and cellular biology

Super-resolution microscopy

All Publications
2023
Tortarolo G., Zunino A., Piazza S., Donato M., Zappone S., Pierzynska-Mach A., Castello M., Vicidomini G.
A Compact and Effective Photon-Resolved Image Scanning Microscope
bioRxiv
DOI 10.1101/2023.07.28.549477
2023
Mariani D., Setti A., Castagnetti F., Vitiello E., Stufera Mecarelli L., di Timoteo G., Giuliani A., Perego E., Zappone S., Vicidomini G., Liessi L., Armirotti A., Bozzoni I.
ALS-associated FUS mutation reshapes the RNA and protein composition and dynamic of Stress Granules
bioRxiv
DOI 10.1101/2023.09.11.557245
Article E-print Archive
2023
Perego E., Zappone S., Slenders E., Castagnetti F., Vitiello E., Mariani D., Mecarelli S. L., Bozzoni I., Vicidomini G.
Comprehensive Fluorescence Lifetime Fluctuation Spectroscopy to investigate protein mobility during aggregation processes in living cells
67th Biophysical Society annual meeting
Abstract Report Conference
2023
Perego E., Zappone S., Castagnetti F., Mariani D., Vitiello E., Rupert J., Zacco E., Tartaglia G.G., Bozzoni I., Slenders E., Vicidomini G.
Content-enriched fluorescence lifetime fluctuation spectroscopy to study bio-molecular condensate formation
bioRxiv
DOI 10.1101/2023.06.09.544221
Article E-print Archive
2023
Zappone S., Perego E., Rupert J., Zacco E., Slenders E., Tartaglia G.G., Vicidomini G.
Deciphering the effect of RNA on alpha-synuclein phase separation with fluorescence fluctuation spectroscopy
European Biopjysical Society Congress
Poster Conference
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Oral presentations
2023
Zappone S., Perego E., Rupert J., Zacco E., Slenders E., Tartaglia G.G., Vicidomini G.
Deciphering the effect of RNA on alpha-synuclein phase separation with fluorescence fluctuation spectroscopy
EBSA satellite meeting: Fluorescence-based fluctuations and single molecule fluorescence
Conference
2022
Zappone S., Perego E., Rupert J., Zacco E., Slenders E., Tartaglia G. G., Vicidomini G.
Fluorescence correlation spectroscopy to determine the role of non-coding RNAs in alpha-synuclein aggregation
XXVI Congresso Nazionale SIBPA 2022
Conference
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Awards and Achievements
2023
Zappone S.
Travel grant SIBPA for EBSA2023
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Colleagues of Molecular Microscopy and Spectroscopy
Giacomo Garre' PhD Student Molecular Microscopy and Spectroscopy
Eli Slenders Researcher Molecular Microscopy and Spectroscopy
Alessandro Zunino Post Doc Molecular Microscopy and Spectroscopy
Andrea Bucci Post Doc Molecular Microscopy and Spectroscopy
Giuseppe Vicidomini Senior Researcher Tenured - Principal Investigator Molecular Microscopy and Spectroscopy
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